• Research

    In vitro bone mechanobiology

    In the area of in vitro mechanobiology of osteocytes, osteoblasts and osteoclasts, we have developed both two-dimensional (2D) and three-dimensional (3D) models for testing a series of novel hypotheses regarding the role of the osteocyte network in sensing mechanical signals and regulating osteoblast or osteoclast functions...
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  • Research

    Quasi-3D cell mechanics

    We have recently developed a novel quasi-3D microscopy system for the study of cells under fluid flow. This novel technology provides an amazing ability to simultaneously visualize and quantify, in real-time and in 3D, the dynamics of two cytoskeletal components and signal activation via fluorescence resonance energy transfer (FRET)...
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  • Research

    ITS and FEA of Skeletons

    In the area of image based microstructural and finite element analyses of human skeletons, we have innovated and advanced an individual trabeculae segmentation (ITS) technique and demonstrated its unique power in basic micromechanics of human trabecular bone...
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Latest from BBL

The BBL held a party to celebrate the approval of a NIH continuation grant application: Micro-Mechanical Modeling of Trabecular Bone. Everyone has done a great job in the submission of the application. Thanks everyone!

  • Learn more about the people that work at the Bone Bioengineering Laboratory.

  • The competitive continuation NIH grant application of ITS project "Micro-Mechanical Modeling of Trabecular Bone" has received an outstanding score of 20 and 7.0% ranking. This is a great news for BBL. Everyone in BBL has worked hard on this. Congratulations!!!

  • Members of BBL celebrated the end of summer at a barbecue at Dr. Guo's house in New Jersey. We grilled some delicious food and enjoyed the company of our fellow labmates!

  • BBL is currently seeking postdocs and Ph.D. students. Check here for more information.

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