• Research

    In vitro bone mechanobiology

    In the area of in vitro mechanobiology of osteocytes, osteoblasts and osteoclasts, we have developed both two-dimensional (2D) and three-dimensional (3D) models for testing a series of novel hypotheses regarding the role of the osteocyte network in sensing mechanical signals and regulating osteoblast or osteoclast functions...
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  • Research

    Quasi-3D cell mechanics

    We have recently developed a novel quasi-3D microscopy system for the study of cells under fluid flow. This novel technology provides an amazing ability to simultaneously visualize and quantify, in real-time and in 3D, the dynamics of two cytoskeletal components and signal activation via fluorescence resonance energy transfer (FRET)...
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  • Research

    ITS and FEA of Skeletons

    In the area of image based microstructural and finite element analyses of human skeletons, we have innovated and advanced an individual trabeculae segmentation (ITS) technique and demonstrated its unique power in basic micromechanics of human trabecular bone...
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Latest from BBL

image image-thumbnail Individual Trabecula Segmentation (ITS) is a powerful 3D image analysis tool for explicit assessments of trabecular plate and rod microstructure, which enables accurate early prediction of changes in metabolic bone diseases and evaluation of drugs that affect bone microstructure.

This software has been made available for download through Columbia Technology Ventures site (http://bit.ly/ColumbiaITS). We are pleased to have more investigators to use ITS in their research and benefit from this valuable technique.

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  • Learn more about the people that work at the Bone Bioengineering Laboratory.

  • No New Position

  • A few members of BBL recently traveled to Suzhou, China for the inaugural International Chinese Musculoskeletal Research Conference (ICMRC) co-sponsored by ICRMS and ASBMR.

    As president of ICMRS, Ed kicked-off the conference, which was a great success.

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